Intrauterine insemination (IUI) is the simplest technique (I level) of Medically Assisted Procreation.
In this technique seminal fluid, duly prepared in the laboratory, is deposited in the uterine cavity.
The purpose of IUI is to increase the density of gametes at the in-vivo fertilization site.
This procedure requires:
- That the patient take drugs for multiple follicular growth for 7 to 10 days
- Ultrasound and/or hormonal monitoring of follicular growth to determine the pharmacological dosage (if hormonal stimulation is needed) and the precise moment of IUI
- Transvaginal transfer to the uterus of the spermatozoa treated by means of a thin catheter.
Intrauterine Insemination is done at the outpatient clinic. It is painless and does not require any particular precautions by the patient.
This technique may be indicated in cases of:
- Idiopathic infertility
- Mild and moderate male factor infertility
- Mild and moderate endometriosis
- Psychological factor
- Erectile dysfunction
- Retrograde ejaculation
Tubal Patency and the absence of structural impediments in the tubes, is essential.
The results that can be obtained in terms of pregnancy rates vary between 5% and 25% (3 cycles of treatment) and depend on:
- Woman’s age
- Number of follicles obtained after ovarian stimulation
- Etiology and duration of infertility
- Quality and number of spermatozoa selected after preparation (IMC – inseminating motile count)